Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443707 | 0.86 | MEN1 (0.42) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11017176 | 0.85 | MEN1 (0.60) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9332431 | 0.84 | KMT2A (0.45) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11195406 | 0.84 | MEN1 (0.47) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10443547 | 0.84 | THRB (0.34) | PKMLMNATHRB | |
| SCHEMBL11188202 | 0.81 | TDP1 (0.49) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10989931 | 0.81 | TDP1 (0.49) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10996557 | 0.80 | TDP1 (0.46) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9134954 | 0.80 | TDP1 (0.50) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8693593 | 0.80 | MEN1 (0.50) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355049-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1990-02-21 | — | — | EP | disclosed |