SCHEMBL10443852

SCHEMBL10443852

COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BIRC2 Q13490 1/20 0.65
▸ OPRK1 P41145 1/20 0.60
▸ LTA4H P09960 1/20 0.60
▸ ANPEP P15144 1/20 0.59
▸ ALDH1A1 P00352 1/20 0.59
▸ THRB P10828 1/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ MME P08473 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29046832 1.00 BIRC2 (0.65) BIRC2OPRK1LTA4HANPEPALDH1A1
SCHEMBL10443850 1.00 BIRC2 (0.65) BIRC2OPRK1LTA4HANPEPALDH1A1
SCHEMBL23106759 1.00 BIRC2 (0.65) BIRC2OPRK1LTA4HANPEPALDH1A1
Hydrochloric Acid SCHEMBL28611123 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Hydrochloric Acid SCHEMBL5500035 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Hydrochloric Acid SCHEMBL10443261 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Hydrochloric Acid SCHEMBL5500030 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Hydrochloric Acid SCHEMBL11594408 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Acetic Acid SCHEMBL10444079 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1
Acetic Acid SCHEMBL10444077 0.99 BIRC2 (0.64) BIRC2OPRK1LTA4HANPEPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166693-A1 METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPY 1 Design Therapeutics, Inc. 2024-05-23 — — US disclosed
CN-117279636-A Methods and compounds for modulating myotonic muscular dystrophy type 1 设计治疗公司 2023-12-22 — — CN disclosed
CN-117229350-A 4-fluoro-indoline compound and preparation method and application thereof 曲阜师范大学 2023-12-15 — — CN disclosed
EP-4259133-A1 METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 Design Therapeutics, Inc. (US) 2023-10-18 — — EP disclosed
CN-116554068-A Preparation method of thio-polypeptide 西安交通大学 2023-08-08 — — CN disclosed
WO-2022126000-A1 METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 Design Therapeutics, Inc. (US) 2022-06-16 — — WO disclosed
CN-101235078-B Method for generating amido bond UNIV XIAMEN 2010-08-25 — — CN disclosed
CN-101235078-A Method for generating amido bond UNIV XIAMEN (CN) 2008-08-06 — — CN disclosed
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166693-A1 METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPY 1 MTPN, DMPK, MBNL1 BIRC2 2397/4885OPRK1 1730/4885LTA4H 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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