MBNL1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL14857435	0.44	2/20
SCHEMBL2125995	1.00	1/20
SCHEMBL16123426	0.85	1/20
SCHEMBL7869225	0.81	1/20
SCHEMBL20087027	0.80	1/20
SCHEMBL20087053	0.80	1/20
SCHEMBL20087077	0.80	1/20
SCHEMBL7880398	0.78	1/20
SCHEMBL17874520	0.77	1/20
SCHEMBL18163852	0.77	1/20
SCHEMBL7875793	0.76	1/20
SCHEMBL2996028	0.75	1/20
SCHEMBL12057934	0.75	1/20
SCHEMBL18163846	0.75	1/20
SCHEMBL18163854	0.75	1/20
SCHEMBL18163881	0.75	1/20
SCHEMBL18163882	0.75	1/20
SCHEMBL18163887	0.75	1/20
SCHEMBL23795497	0.75	1/20
SCHEMBL8845400	0.74	1/20

Clinical trials — most relevant to MBNL1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM	PHASE3	COMPLETED
A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of BBM-D101 in the Treatment of Duchenne Muscular Dystrophy.	PHASE1/PHASE2	RECRUITING
Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy	EARLY_PHASE1	RECRUITING
Molecular and Genetic Studies of Congenital Myopathies	nan	RECRUITING
Overcoming TWEAK Signaling to Restore Muscle and Mobility After Joint Replacement	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China	nan	ENROLLING_BY_INVITATION
Molecular Analysis of Patients With Neuromuscular Disease	nan	RECRUITING
Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)	nan	RECRUITING
Extracellular RNA Biomarkers of Myotonic Dystrophy	nan	RECRUITING
Myotubular and Centronuclear Myopathy Patient Registry	nan	RECRUITING
Genetics of Cardiovascular and Neuromuscular Disease	nan	RECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Influence of Sarcopenia on the Course of the Diseases	nan	RECRUITING
Evaluation of the Role of miR-1 in the Pathogenesis and as a Biomarker in Muscular Dystrophies and Congenital Myopathies	nan	RECRUITING
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations	nan	UNKNOWN
Molecular Profile of the Evolution of Inclusion Body Myositis	nan	COMPLETED
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome	nan	COMPLETED
DMCRN-02-001: Assessing Pediatric Endpoints in DM1	nan	RECRUITING
Improvements in Aerobic Fitness With Exercise Training: the Role of Myokines	nan	COMPLETED
Changes of microRNA Expression in Obstructive and Neurogenic Bladder Dysfunction	nan	COMPLETED
High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia	nan	RECRUITING
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies	nan	RECRUITING
Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases	nan	RECRUITING
Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy	nan	RECRUITING
Differential Study of Muscle Transcriptome	nan	COMPLETED
Cerebellar Mutism Syndrome Study	nan	RECRUITING
Biomarkers in Patients With Advanced Rhabdomyosarcoma	nan	COMPLETED
Genetic Characterization of Individuals With Limb Girdle Muscular Dystrophy	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MBNL1 binder may also engage these)

Protein	Name	Similarity
Q5ZKW9	—	1.000	Q5ZKW9 →
Q6Q2B2	—	1.000	Q6Q2B2 →
Q9JKP5	—	1.000	Q9JKP5 →
F2Z3T4	—	0.999	F2Z3T4 →
Q8C181	—	0.998	Q8C181 →
Q9NUK0	—	0.997	Q9NUK0 →
A0A8I6B1J2	—	0.997	A0A8I6B1J2 →
Q5R4F5	—	0.995	Q5R4F5 →
Q56V19	—	0.994	Q56V19 →
Q8R003	—	0.994	Q8R003 →
Q5VZF2	—	0.990	Q5VZF2 →
A8XND8	—	0.990	A8XND8 →
Q94250	—	0.984	Q94250 →
O01367	—	0.974	O01367 →
Q9BJZ5	—	0.972	Q9BJZ5 →
B4HUE4	—	0.970	B4HUE4 →
B3NGA1	—	0.970	B3NGA1 →
B4LFQ9	—	0.969	B4LFQ9 →
G5EFF1	—	0.968	G5EFF1 →
Q91WT8	—	0.968	Q91WT8 →
B4KX02	—	0.968	B4KX02 →
B4PIS2	—	0.968	B4PIS2 →
B4MM23	—	0.966	B4MM23 →
Q0V9L3	—	0.965	Q0V9L3 →
Q5NVC8	—	0.965	Q5NVC8 →
Q9YH18	—	0.965	Q9YH18 →
Q9GMY1	—	0.965	Q9GMY1 →
Q7JJZ8	—	0.965	Q7JJZ8 →
Q66H68	—	0.965	Q66H68 →
Q5W9D6	—	0.965	Q5W9D6 →