SCHEMBL10444093

SCHEMBL10444093

CC(C)CNC(=O)CC(O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CC1COc2ccc([N+](=O)[O-])cc21

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10443676 1.00 REN (0.48) REN
Water SCHEMBL10443702 0.99 REN (0.47) REN
SCHEMBL10444394 0.92 REN (0.50) REN
SCHEMBL10443898 0.91 REN (0.49) REN
SCHEMBL10443786 0.91 REN (0.50) REN
SCHEMBL10443434 0.90 REN (0.58) REN
Hydrochloric Acid SCHEMBL10444229 0.90 REN (0.49) REN
SCHEMBL10443949 0.90 REN (0.49) REN
SCHEMBL10444091 0.89 REN (0.43) REN
Water SCHEMBL10443699 0.88 REN (0.42) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 — — EP disclosed
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