Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443998 | 0.91 | REN (0.44) | REN | |
| SCHEMBL10443703 | 0.91 | REN (0.49) | REN | |
| SCHEMBL10444219 | 0.90 | REN (0.49) | REN | |
| SCHEMBL10443644 | 0.87 | REN (0.45) | REN | |
| SCHEMBL10444393 | 0.86 | REN (0.37) | REN | |
| SCHEMBL10444286 | 0.86 | REN (0.44) | REN | |
| SCHEMBL10444209 | 0.85 | REN (0.45) | REN | |
| SCHEMBL10443682 | 0.85 | REN (0.44) | REN | |
| SCHEMBL10443630 | 0.85 | REN (0.45) | REN | |
| SCHEMBL10443894 | 0.85 | BACE1 (0.37) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | claimed |
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | disclosed |