SCHEMBL10444241

SCHEMBL10444241

CC(=O)N(C1COc2ccc(C=O)cc21)[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NC(CC1CCCCC1)C(O)CC(=O)NCC(C)C

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10444221 0.92 REN (0.44) REN
SCHEMBL10444091 0.91 REN (0.43) REN
Water SCHEMBL10443699 0.90 REN (0.42) REN
SCHEMBL10444159 0.90 REN (0.50) REN
Water SCHEMBL10443800 0.90 REN (0.49) REN
Water SCHEMBL10444472 0.89 REN (0.42) REN
SCHEMBL10443786 0.89 REN (0.50) REN
SCHEMBL10444211 0.82 REN (0.50) REN
SCHEMBL10444394 0.82 REN (0.50) REN
SCHEMBL10443626 0.82 REN (0.54) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 — — EP disclosed
Send feedback