Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136252 | 0.85 | COMT (0.56) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8136432 | 0.82 | PTPN11 (0.41) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Bromide SCHEMBL9290785 | 0.81 | PTPN11 (0.40) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8138025 | 0.74 | COMT (0.47) | — | |
| SCHEMBL8130166 | 0.72 | COMT (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8119797 | 0.72 | COMT (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8137012 | 0.72 | COMT (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8137123 | 0.72 | COMT (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL6901759 | 0.71 | COMT (0.60) | PTPN11 | |
| SCHEMBL6901895 | 0.70 | COMT (0.46) | LMNAPTPN11ALDH1A1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354495-A1 | Alkoxy-4(1H)-pyridone derivatives, process for their preparation and their pharmaceutical use | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-02-14 | — | — | EP | disclosed |