SCHEMBL10445929

SCHEMBL10445929

COc1ccc2cc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5cccc6ccccc56)cc4)cc3)ccc2c1-c1c(C=O)ccc2cc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5cccc6ccccc56)cc4)cc3)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ERN1 O75460 5/20 0.37
KDM4E B2RXH2 2/20 0.37
SLC16A3 O15427 1/20 0.36
SLC16A1 P53985 1/20 0.36
EGFR P00533 1/20 0.36
PDGFRB P09619 1/20 0.36
KDR P35968 1/20 0.36
ALOX5 P09917 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
ABCB1 P08183 2/20 0.33
ABCC1 P33527 2/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447383 0.91 MAPT (0.50) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL10445930 0.84 SLC16A3 (0.40) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL12012666 0.84 MAPT (0.42) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL18071635 0.78 CYP1A2 (0.44) MAPTALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL18071636 0.78 CYP1A2 (0.44) MAPTALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL14070366 0.78 ALDH1A1 (0.39) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL14070315 0.78 ALDH1A1 (0.39) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL14070352 0.78 ALDH1A1 (0.39) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL14070346 0.78 ALDH1A1 (0.39) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL14070357 0.78 ALDH1A1 (0.39) MAPTALDH1A1KDM4EL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222807-B2 Organic electroluminescence device and method of producing organic device MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-17 US disclosed
US-20100090590-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND METHOD OF PRODUCING ORGANIC DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-04-15 US disclosed