SCHEMBL10445941

SCHEMBL10445941

CC(C)(C)OC(=O)OC1CC(=O)N(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 10/20 0.37
STS P08842 1/20 0.36
RECQL P46063 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
CETP P11597 1/20 0.34
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446268 0.87 STS (0.38) TACR1STSCETP
SCHEMBL10446144 0.85 RECQL (0.39) TACR1RECQLSMN1; SMN2LMNAMEN1
SCHEMBL9731544 0.80 RECQL (0.46) STSRECQLSMN1; SMN2MEN1POLB
SCHEMBL10445910 0.76 ACACB (0.36) TACR1STSPOLBKMT2ACETP
SCHEMBL11748158 0.73 CA1 (0.58) RECQLSMN1; SMN2MEN1POLBKMT2A
SCHEMBL5841909 0.72 RECQL (0.62) RECQLSMN1; SMN2MEN1POLBKMT2A
SCHEMBL11747018 0.71 RECQL (0.47) RECQLSMN1; SMN2MEN1POLBKMT2A
Hydrochloric Acid SCHEMBL11747023 0.71 RECQL (0.61) RECQLSMN1; SMN2MEN1POLBKMT2A
SCHEMBL10445947 0.71 FFAR4 (0.34) TACR1STS
SCHEMBL11743250 0.71 RECQL (0.47) RECQLSMN1; SMN2MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397602-A1 N-phenylpyrrolidines CIBA-GEIGY AG (CH) 1990-11-14 EP disclosed