Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445910 | 0.86 | ACACB (0.36) | NOTUMTACR1GPR35STSALDH1A1 | |
| SCHEMBL10446144 | 0.85 | RECQL (0.39) | FFAR4NOTUMLIPGTACR1 | |
| SCHEMBL10446268 | 0.85 | STS (0.38) | FFAR4TACR1STS | |
| SCHEMBL9731676 | 0.80 | NOTUM (0.44) | FFAR4NOTUMCES2 | |
| SCHEMBL9731353 | 0.75 | CA1 (0.43) | NOTUMTACR1STSALDH1A1GAA | |
| SCHEMBL9731532 | 0.74 | STS (0.42) | FFAR4NOTUMTACR1STS | |
| SCHEMBL10445909 | 0.73 | DPP4 (0.39) | ADRB1 | |
| SCHEMBL9846416 | 0.71 | GRM2 (0.41) | FFAR4NOTUMTACR1CES2ADRB1 | |
| SCHEMBL10445941 | 0.71 | TACR1 (0.37) | TACR1STS | |
| SCHEMBL5841909 | 0.67 | RECQL (0.62) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | claimed |
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |