Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446240 | 0.90 | DYRK1A (0.48) | DYRK1ADYRK1BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL10446237 | 0.89 | DYRK1A (0.45) | DYRK1ADYRK1BALDH1A1L3MBTL1MAPT | |
| SCHEMBL10446629 | 0.81 | DYRK1A (0.45) | DYRK1ADYRK1BALDH1A1L3MBTL1POLB | |
| SCHEMBL10321615 | 0.79 | RAB9A (0.50) | DYRK1ADYRK1BRAB9AALDH1A1TDP1 | |
| SCHEMBL10330656 | 0.74 | GPR17 (0.54) | DYRK1ADYRK1BRAB9AALDH1A1TDP1 | |
| SCHEMBL10322470 | 0.74 | RAB9A (0.43) | DYRK1ADYRK1BRAB9AALDH1A1TDP1 | |
| SCHEMBL10323421 | 0.74 | POLB (0.48) | DYRK1ADYRK1BRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL10322342 | 0.73 | POLB (0.47) | DYRK1ADYRK1BRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL21639501 | 0.73 | RAB9A (0.51) | DYRK1ADYRK1BRAB9AALDH1A1HPGD | |
| SCHEMBL10446512 | 0.73 | KDM4E (0.41) | DYRK1ADYRK1BALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | TYMS, TYMP, DPYD | DYRK1A 654/4885DYRK1B 570/4885RAB9A 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.