Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 13/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 13/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446762 | 0.84 | UBE2M (0.52) | UBE2MDCUN1D1POLBHTTTP53 | |
| SCHEMBL10447090 | 0.84 | HTT (0.45) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10446648 | 0.83 | UBE2M (0.51) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10447161 | 0.82 | UBE2M (0.49) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10446649 | 0.82 | UBE2M (0.46) | UBE2MDCUN1D1POLBRAB9APPARG | |
| SCHEMBL10446828 | 0.82 | UBE2M (0.50) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10446813 | 0.82 | UBE2M (0.50) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10447008 | 0.80 | UBE2M (0.46) | UBE2MDCUN1D1HTTPPARGPPARD | |
| SCHEMBL10446628 | 0.80 | UBE2M (0.49) | UBE2MDCUN1D1POLBRAB9AHTT | |
| SCHEMBL10446781 | 0.79 | UBE2M (0.47) | UBE2MDCUN1D1RAB9AHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |