Sugi Predict
/ Targets
/ UBE2M
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to UBE2M by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) Syndrome |
PHASE2/PHASE3 | NOT_YET_RECRUITING |
| Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With Angelman Syndrome (AS) |
PHASE3 | ACTIVE_NOT_RECRUITING |
| MLN9708 and Dexamethasone for High-Risk Smoldering Multiple Myeloma |
PHASE2 | WITHDRAWN |
| UB-621, a New Type of Anti-herpes Simplex Virus (HSV) Monoclonal Antibody for the Use in the Treatment of Adult Recurrent HSV-2 Infections of the Genitals |
PHASE2 | UNKNOWN |
| Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy |
PHASE2 | ACTIVE_NOT_RECRUITING |
| MLN9708 for the Prophylaxis of Chronic Graft-versus-host Disease in Patient Undergoing Allogeneic Transplantation |
PHASE1/PHASE2 | COMPLETED |
| Personalized Antisense Oligonucleotide for A Single Participant With UBTF Gene Mutation |
PHASE1/PHASE2 | ACTIVE_NOT_RECRUITING |
| Evaluate the Safety, Tolerability, Immunogenicity and Efficacy of UB-311 in Mild Alzheimer's Disease (AD) Patients |
PHASE2 | COMPLETED |
| Olaparib in Patients With HRD Malignant Mesothelioma |
PHASE2 | RECRUITING |
| Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma |
PHASE2 | SUSPENDED |
| A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity |
PHASE2 | RECRUITING |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS) |
PHASE1 | COMPLETED |
| Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy Volunteers |
PHASE1 | COMPLETED |
| UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis |
PHASE1 | RECRUITING |
| Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome |
PHASE1 | COMPLETED |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-612 COVID-19 Vaccine |
PHASE1 | COMPLETED |
| Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease |
EARLY_PHASE1 | RECRUITING |
| Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis |
nan | UNKNOWN |
| The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin |
nan | UNKNOWN |
| Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors |
nan | NOT_YET_RECRUITING |
| Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) |
nan | UNKNOWN |
| A Natural History Study of Angelman Syndrome |
nan | RECRUITING |
| Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 |
nan | RECRUITING |
| HRQoL and Financial Toxicity in Patients With VEXAS Syndrome |
nan | RECRUITING |
| Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure |
nan | COMPLETED |
| Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2 |
nan | NOT_YET_RECRUITING |
| Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2 |
nan | UNKNOWN |
| Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome |
nan | RECRUITING |
| Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas |
nan | RECRUITING |
| Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a UBE2M binder may also engage these)