SCHEMBL104469

SCHEMBL104469

CC(=O)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25507692 1.00
Acetic Acid SCHEMBL27365333 0.91 FFAR3 (0.58)
SCHEMBL5219014 0.80
SCHEMBL27955866 0.80
SCHEMBL519 0.78
SCHEMBL298778 0.78
SCHEMBL1331921 0.78
SCHEMBL5180151 0.78
SCHEMBL11026359 0.78
SCHEMBL1331275 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2289 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290459-A Preparation and application of spiral photosensitizer for directionally inducing cell apoptosis 南开大学 2024-07-05 CN claimed
CN-118290458-A Preparation method and application of biocompatible BODIPY-based near-infrared photosensitizer 南开大学 2024-07-05 CN claimed
WO-2024120275-A1 PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF 浙江华海药业股份有限公司 2024-06-13 WO claimed
CN-114349693-B Preparation method of dolutegravir key intermediate 瑞孚信江苏药业股份有限公司 2024-03-22 CN claimed
CN-113461573-B Preparation method of (2S) -substituted-3-deuterium-L-valine ester 南京迈诺威医药科技有限公司 2022-11-15 CN claimed
US-20220220061-A1 PROCESS FOR THE SYNTHESIS OF THE IONIC LIQUID TETRAOCTYLAMMONIUM DI(2-ETHYLHEXYL)-OXAMATE (IL-5), PRODUCT OBTAINED AND ITS USE IN SELECTIVE METAL EXTRACTION INSTITUTO SUPERIOR TÉCNICO (PT) 2022-07-14 US claimed
CN-111943887-B Fluorescent probe for high-selectivity recognition of phosphate, preparation method and application 济南大学 2022-06-24 CN claimed
CN-114349693-A Preparation method of dolutegravir key intermediate 瑞孚信江苏药业股份有限公司 2022-04-15 CN claimed
CN-114014819-A Preparation method of 1,4,8, 11-tetraazacyclotetradecane 武汉弯豆科技有限公司 2022-02-08 CN claimed
CN-113666826-A Method for methoxylation of aryl or heteroaryl 五邑大学 2021-11-19 CN claimed
WO-2005072082-A2 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2005-08-11 WO claimed
US-20050148645-A1 2-Guanidinylimidazolidinedione compounds and methods of making and using thereof ARMY, UNITED STATES 2005-07-07 US claimed
WO-2005049614-A2 PROCESSES FOR PREPARING TETRAHYDROBIOPTERIN, AND ANALOGS OF TETRAHYDROBIOPTERIN BIOMARIN PHARMACEUTICAL INC. (US) 2005-06-02 WO claimed
CN-1542001-A Small molecule inhibitors of rotamase enzyme activity GPI����عɹ�˾ 2004-11-03 CN claimed
EP-0992492-B1 Small molecule inhibitors of rotamase enzyme activity GUILFORD PHARM INC (US) 2004-08-25 EP claimed
EP-1433781-A1 Pyrrolidine carboxylic acid derivatives GPI NIL Holdings, Inc. (US) 2004-06-30 EP claimed
EP-0992492-A1 Small molecule inhibitors of rotamase enzyme activity GUILFORD PHARMACEUTICALS INC. (US) 2000-04-12 EP claimed
CN-1127757-A Novel tetrahydropyran compounds, their preparation and pharmaceutical compositions containing them ADIR (FR) 1996-07-31 CN claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
US-4620010-A Process for preparing carboalkoxy substituted benzoxazole compounds USV PHARMACEUTICAL CORP. (US) 1986-10-28 US claimed