⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104469 | 0.80 | — | — | |
| SCHEMBL25507692 | 0.80 | — | — | |
| SCHEMBL5180151 | 0.78 | — | — | |
| SCHEMBL298778 | 0.78 | — | — | |
| Acetone SCHEMBL27692287 | 0.78 | — | — | |
| SCHEMBL519 | 0.78 | — | — | |
| SCHEMBL1331275 | 0.78 | — | — | |
| SCHEMBL11026359 | 0.78 | — | — | |
| SCHEMBL1331921 | 0.78 | — | — | |
| SCHEMBL1331666 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |
| US-6645968-B2 | E.g., N-(1-((anilinocarbonyl)amino)-2,2,2-trichloroethyl)-4-methyl-benzamide; antiepileptic, -ischemic and cardiotonic agents; sexual, eating and urogenital disorders; asthma; migraines; | ABBOTT LABORATORIES | 2003-11-11 | — | — | US | disclosed |
| US-6495576-B2 | N-(1-((3,4-DIOXO-2-(3-PYRIDINYLAMINO)-1-CYCLOBUTEN-1-YL)AMINO) -2,2-DIMETHYLPROPYL)-4-METHYLBENZAMIDE FOR EXAMPLE; TREATING BLADDER OVERACTIVITY, BENIGN PROSTATIC HYPERPLASIA, PREMATURE LABOR, AND SEXUAL DISORDERS | ABBOTT LABORATORIES | 2002-12-17 | — | — | US | disclosed |
| US-20020165264-A1 | Aminal diones as potassium channel openers | ABBOTT LABORATORIES | 2002-11-07 | — | — | US | disclosed |
| US-20020147230-A1 | Aminal Diones as potassium channel openers | ABBOTT LABORATORIES | 2002-10-10 | — | — | US | disclosed |
| US-20020028836-A1 | Potassium channel openers | ABBVIE INC. | 2002-03-07 | — | — | US | disclosed |
| US-5684127-A | SELECTIVELY PROTECTING AMINO GROUPS AND PHENOLIC HYDROXY GROUPS OF A PENTAPEPTIDE, OXIDIZING THE HYDROXYMETHYL MOIETY OF PROTECTED PENTAPEPTIDE TO CARBOXY, DEPROTECTING AMINO GROUP AND SUBMITTING COMPOUND TO DEGRADATION | GRUPPO LEPETIT SPA (IT) | 1997-11-04 | — | — | US | disclosed |
| US-5644025-A | AGLYCON DALBAHEPTIDE ANTIBIOTICS FOR CYCLIC TETRAPEPTIDES FOR BACTERICIDES | GRUPPO LEPETIT SPA (IT) | 1997-07-01 | — | — | US | disclosed |
| EP-0561827-B1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | LEPETIT SPA (IT) | 1995-04-12 | — | — | EP | disclosed |
| EP-0561827-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS. | LEPETIT SPA (IT) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010517-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1992-06-25 | — | — | WO | disclosed |