Sugi Predict

Sugi Predict / Compounds / SCHEMBL104470

SCHEMBL104470

SCHEMBL104470

O=[N+]([O-])c1c(F)cc(F)cc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.52
▸ ATM Q13315 1/20 0.52
▸ ALDH1A1 P00352 3/20 0.41
▸ TSHR P16473 2/20 0.41
▸ HIF1A Q16665 1/20 0.40
▸ ABCC8 Q09428 1/20 0.39
▸ KCNJ11 Q14654 1/20 0.39
▸ HSPB1 P04792 3/20 0.39
▸ TTR P02766 2/20 0.39
▸ P2RY6 Q15077 1/20 0.39
▸ GRIN2D O15399 3/20 0.38
▸ GRIN3B O60391 3/20 0.38
▸ GRIN1 Q05586 3/20 0.38
▸ GRIN2A Q12879 3/20 0.38
▸ GRIN2B Q13224 3/20 0.38
▸ GRIN2C Q14957 3/20 0.38
▸ GRIN3A Q8TCU5 3/20 0.38
▸ VCAM1 P19320 1/20 0.38
▸ CYP3A4 P08684 1/20 0.37
▸ ARNT P27540 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29745076 0.86 TDP1 (0.45) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL4647699 0.86 TDP1 (0.55) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL1708265 0.86 TDP1 (0.45) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL29833735 0.84 TTR (0.45) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL1680932 0.84 TTR (0.45) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL9000095 0.84 ATM (0.44) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL20241509 0.84 TDP1 (0.44) TDP1ATMALDH1A1TSHRABCC8
SCHEMBL28436740 0.84 ATM (0.44) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL28084778 0.84 TDP1 (0.44) TDP1ATMALDH1A1TSHRHIF1A
SCHEMBL2548910 0.82 CYP19A1 (0.50) TDP1ATMALDH1A1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096123-B Novel compound 6-fluoro-2, 4-diaminonitrobenzene and preparation method thereof 郑州轻工业学院 2021-01-26 — — CN claimed
CN-109096123-A A kind of fluoro- 2,4- diamino nitrobenzene of new compound 6- and preparation method thereof 郑州轻工业学院 2018-12-28 — — CN claimed
US-9870909-B2 Compositions and methods for mass spectometry MSTM, LLC 2018-01-16 — — US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 — — US claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 — — WO disclosed
US-20260125366-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS INC (US) 2026-05-07 — — US disclosed
WO-2026087650-A1 VINYLOXY-ARYL COMPOUNDS FOR THE TREATMENT OF CANCER SANOFI (FR) 2026-04-30 — — WO disclosed
US-20260102406-A1 SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY NEUPHARMA INC (US) 2026-04-16 — — US disclosed
US-12600703-B2 Methods of synthesizing farnesyl dibenzodiazepinones AMO PHARMA LTD. (GB) 2026-04-14 — — US disclosed
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 — — EP disclosed
US-20260042788-A1 STAT6 COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-12 — — US disclosed
EP-3508204-B1 QUINAZOLIN-8-YL DERIVATIVES FOR USE IN METHODS OF TREATING MELANOMA, NON-SMALL CELL LUNG CANCER, THYROID CANCER, OVARIAN CANCER, OR COLON CANCER NEUPHARMA INC (US) 2026-02-11 — — EP disclosed
US-4059434-A Cycloalkanapyrazole herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-11-22 — — US disclosed
US-4032326-A HERBICIDAL 2-SUBSTITUTED ARYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 — — US disclosed
US-4003926-A Herbicidal 2-arylaminocarbonyl-1-cyclohexene-1-carboxylic acids and salts thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-18 — — US disclosed
US-4001272-A HERBICIDAL 2-FLUORO-4-HALO-PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-04 — — US disclosed
US-3992189-A Herbicidal isoindol-1-one derivatives E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-11-16 — — US disclosed
US-3990880-A Herbicidal isobenzofuranones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 — — US disclosed
US-3987057-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 — — US disclosed
US-3958976-A 2-Aryl-5,6,7,8-tetrahydroimidazo[1,5a]-pyridine-1,3(2H,8aH)-diones as herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042788-A1 STAT6 COMPOUNDS STAT6, IL6ST, NFATC1 TDP1 3845/4885ATM 1978/4885ALDH1A1 1587/4885
US-20260125366-A1 METHODS FOR TREATING CANCER AKT2, AKT3, PIK3R5 TDP1 683/4885ATM 1342/4885ALDH1A1 2246/4885
US-12600703-B2 Methods of synthesizing farnesyl dibenzodiazepinones NR1H2, NR1H3, NR1H4 TDP1 4337/4885ATM 3639/4885ALDH1A1 1762/4885
US-20260102406-A1 SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY BRAF, TTK, MAP4K2 TDP1 1468/4885ATM 102/4885ALDH1A1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.