Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023090 | 0.86 | TSHR (0.55) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL20709266 | 0.78 | TSHR (0.46) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL9397850 | 0.77 | TSHR (0.50) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL1967414 | 0.75 | TSHR (0.46) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL19200293 | 0.72 | TSHR (0.55) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL2230579 | 0.72 | TSHR (0.55) | TSHRMAPTNPC1RAB9AACHE | |
| SCHEMBL19981757 | 0.72 | TSHR (0.55) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL9668570 | 0.71 | KIF11 (0.49) | TSHRKIF11ACHEESR1ESR2 | |
| SCHEMBL10576971 | 0.71 | TSHR (0.60) | TSHRMAPTNPC1RAB9AKIF11 | |
| SCHEMBL6280416 | 0.70 | KMT2A (0.52) | TSHRKIF11ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |