Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.57 |
| ▸ | LSS | P48449 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754552 | 0.88 | MEN1 (0.84) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL10589292 | 0.86 | ALDH1A1 (0.86) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9485046 | 0.82 | MEN1 (0.75) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9754483 | 0.82 | MEN1 (0.75) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9329691 | 0.82 | MEN1 (0.75) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9128700 | 0.81 | MEN1 (0.65) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL8840166 | 0.81 | TBXA2R (0.64) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL1368550 | 0.81 | MEN1 (0.73) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9754209 | 0.81 | MEN1 (0.73) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 | |
| SCHEMBL28897034 | 0.81 | ALDH1A1 (0.84) | MEN1KMT2ATBXA2RALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356989-A2 | Sulfon amides with a tetrazolyl rest, process for their preparation an therapeutic agents | Roche Diagnostics GmbH (DE) | 1990-03-07 | — | — | EP | disclosed |