Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316924 | 0.84 | KDM4E (0.60) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL10058004 | 0.82 | HRH3 (0.62) | KDM4EPPARAPPARGHRH3HPGD | |
| SCHEMBL3761024 | 0.82 | KDM4E (0.58) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL266619 | 0.82 | KDM4E (0.66) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL2979513 | 0.79 | HRH3 (0.59) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL13721983 | 0.79 | PPARG (0.65) | PPARAPPARG | |
| SCHEMBL5480570 | 0.78 | PPARA (0.52) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL5478651 | 0.77 | PPARA (0.48) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL503999 | 0.77 | KDM4E (0.64) | KDM4ELMNAPPARAPPARGHRH3 | |
| SCHEMBL4037331 | 0.77 | KDM4E (0.69) | KDM4ELMNAPPARAPPARGHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389699-A1 | Thiazolidinedione derivatives as hypoglycemic agents | PFIZER INC. (US) | 1990-10-03 | — | — | EP | disclosed |