Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351068 | 0.80 | HPGD (0.58) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL11315321 | 0.79 | LOXL2 (0.53) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL27263671 | 0.78 | HPGD (0.49) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL8413104 | 0.77 | HPGD (0.54) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL20072395 | 0.77 | LOXL2 (0.62) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL5687666 | 0.75 | HPGD (0.60) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10352168 | 0.74 | LOXL2 (0.54) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL27943317 | 0.74 | HPGD (0.59) | HPGDLOXL2MAPK9MAPK10HSD17B10 | |
| SCHEMBL21275558 | 0.73 | LOXL2 (0.62) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL27352412 | 0.73 | HPGD (0.54) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359036-A1 | Fumagillol derivatives | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |