⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19899968 | 1.00 | TSHR (0.41) | — | |
| SCHEMBL27905398 | 0.97 | — | — | |
| SCHEMBL15955896 | 0.88 | — | — | |
| SCHEMBL28305438 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL7155300 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL9007915 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL25996485 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL28763518 | 0.82 | TSHR (0.32) | — | |
| SCHEMBL28537177 | 0.82 | TSHR (0.52) | — | |
| SCHEMBL14306294 | 0.81 | CES2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-A1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | Roche Diagnostics GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |