Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917076 | 0.92 | HTT (0.51) | HTTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL2921263 | 0.92 | HTT (0.51) | HTTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL7271033 | 0.86 | KMT2A (0.52) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13774925 | 0.85 | KMT2A (0.47) | HTTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8915981 | 0.84 | HTT (0.50) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7417244 | 0.81 | MEN1 (0.46) | HTTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL7417247 | 0.81 | MEN1 (0.46) | HTTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL1399017 | 0.81 | HTT (0.50) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1399018 | 0.81 | HTT (0.50) | HTTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7286337 | 0.81 | HTT (0.50) | HTTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363856-A1 | Derivative of coumarin, process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-18 | — | — | EP | disclosed |