Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417247 | 1.00 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AITGB3 | |
| SCHEMBL7385326 | 0.86 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7271033 | 0.85 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13774925 | 0.84 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9AITGB3 | |
| SCHEMBL2921263 | 0.83 | HTT (0.51) | MEN1KMT2ANPC1RAB9AITGB3 | |
| SCHEMBL2917076 | 0.83 | HTT (0.51) | MEN1KMT2ANPC1RAB9AITGB3 | |
| SCHEMBL10448019 | 0.81 | HTT (0.56) | MEN1KMT2ANPC1RAB9AITGB3 | |
| SCHEMBL8915981 | 0.80 | HTT (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8981083 | 0.79 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8981259 | 0.78 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299963-B1 | RENIN INHIBITORS HAVING A LACTAM PSEUDO DIPEPTIDE | THE UPJOHN COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0299963-A1 | RENIN INHIBITORS HAVING A LACTAM PSEUDO DIPEPTIDE. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4705846-A | Novel renin inhibiting peptides having a gamma lactam pseudo dipeptide insert | THE UPJOHN COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| WO-1987005909-A2 | RENIN INHIBITORS HAVING A LACTAM PSEUDO DIPEPTIDE | THE UPJOHN COMPANY (US) | 1987-10-08 | — | — | WO | disclosed |