SCHEMBL10448403

SCHEMBL10448403

C=CC(=O)/C=C/c1ccccc1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.78
JUN P05412 1/20 0.78
NFE2L2 Q16236 1/20 0.78
GSR P00390 1/20 0.66
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA4 P22748 1/20 0.63
MAPT P10636 3/20 0.61
LMNA P02545 1/20 0.61
MAPK1 P28482 2/20 0.58
KDM4E B2RXH2 1/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
ATM Q13315 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
BCHE P06276 1/20 0.58
GUSB P08236 1/20 0.58
CHRNA7 P36544 3/20 0.53
CDK4 P11802 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448404 1.00 NFKB1 (0.78) NFKB1JUNNFE2L2GSRCA1
SCHEMBL29539991 0.88 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL3329177 0.88 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL1160537 0.88 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL1160535 0.88 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL11408172 0.86 NFKB1 (0.96) NFKB1JUNNFE2L2CA1CA2
SCHEMBL27781268 0.82 NFKB1 (0.81) NFKB1JUNNFE2L2CA1CA2
SCHEMBL4448927 0.80 NFKB1 (0.59) NFKB1JUNNFE2L2CA1CA2
SCHEMBL28827718 0.79 GSR (0.64) NFKB1JUNNFE2L2GSRMAPT
SCHEMBL17068275 0.79 NFKB1 (0.81) NFKB1JUNNFE2L2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371924-A2 Process for making a pattern CIBA-GEIGY AG (CH) 1990-06-06 EP disclosed