Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.38 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435471 | 0.89 | PPARG (0.37) | CYSLTR2CYSLTR1EPHX1ADH1BADH1C | |
| SCHEMBL9560003 | 0.83 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL10448807 | 0.81 | PPARG (0.48) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL10448312 | 0.80 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL10704682 | 0.74 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL10435389 | 0.74 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560302 | 0.73 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL10435614 | 0.72 | PPARG (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL10424207 | 0.72 | PPARG (0.47) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL10448811 | 0.71 | CYP3A4 (0.41) | CYSLTR2CYSLTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358240-A2 | Intermediates for the preparation of leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |