Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703842 | 0.90 | PPARG (0.34) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9484780 | 0.86 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL10448312 | 0.76 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PTGESALOX5PPARG | |
| SCHEMBL10448807 | 0.75 | PPARG (0.48) | CYSLTR2CYSLTR1PPARGALDH1A1 | |
| SCHEMBL10448490 | 0.74 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL10435389 | 0.68 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560009 | 0.68 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1 | |
| SCHEMBL6684349 | 0.67 | CSNK1E (0.42) | CYSLTR2CYSLTR1PPARGALDH1A1 | |
| SCHEMBL10448636 | 0.67 | SLC6A2 (0.38) | ALDH1A1 | |
| SCHEMBL10435614 | 0.67 | PPARG (0.48) | CYSLTR2CYSLTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296731-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |