SCHEMBL10448657

SCHEMBL10448657

Cc1ccc(S(=O)(=O)C(O)COCC(O)c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.51
PIR O00625 1/20 0.50
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
FFAR1 O14842 3/20 0.43
MAOB P27338 2/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8791278 0.84 AR (0.50) ARPIRPDE4APDE4BPDE4C
SCHEMBL2535587 0.83 AR (0.54) ARPIRPDE4APDE4BPDE4C
SCHEMBL8476567 0.83 AR (0.49) ARPIRPDE4APDE4BPDE4C
SCHEMBL3271450 0.76 AR (0.56) ARPIRPDE4APDE4BPDE4C
SCHEMBL9018766 0.75 CA12 (0.55) ARPDE4APDE4BPDE4CPDE4D
SCHEMBL3274194 0.74 AR (0.57) ARPIRPDE4APDE4BPDE4C
SCHEMBL11686413 0.73 AR (0.55) ARPIRCA12CA1CA2
SCHEMBL7429844 0.73 AR (0.55) ARPIRCA12CA1CA2
SCHEMBL8483093 0.72 LMNA (0.50) FFAR1MAOBNPC1LMNAMAPT
SCHEMBL13588852 0.71 CA12 (0.64) ARPIRPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383281-A1 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1990-08-22 EP disclosed