Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.69 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482240 | 0.81 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559866 | 0.79 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1FFAR1MAPTRXFP1 | |
| SCHEMBL10815496 | 0.76 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1FFAR1MAPTRXFP1 | |
| SCHEMBL10482208 | 0.74 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1FFAR1MAPTRXFP1 | |
| SCHEMBL10482210 | 0.74 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1FFAR1PLA2G4BMAPT | |
| SCHEMBL9244930 | 0.73 | MAPT (0.54) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9244921 | 0.73 | MAPT (0.54) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL10482137 | 0.68 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL10482248 | 0.68 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL27588900 | 0.68 | FFAR1 (0.69) | CYSLTR2CYSLTR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358240-A2 | Intermediates for the preparation of leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |