Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12184237 | 0.86 | CYP2C19 (0.70) | CYP2C19CYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL6212293 | 0.85 | CYP2C9 (0.88) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6211538 | 0.82 | CYP1A2 (0.78) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6212608 | 0.81 | HSD11B1 (0.74) | CYP2C19HSD11B1SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL6236172 | 0.79 | HSD11B1 (1.00) | HSD11B1SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL3044364 | 0.79 | HSD11B1 (0.77) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27943800 | 0.78 | HSD11B1 (0.74) | HSD11B1SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL3391936 | 0.77 | HSD11B1 (0.69) | HSD11B1MGLL | |
| SCHEMBL28051082 | 0.77 | HSD11B1 (0.68) | CYP2C19HSD11B1SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL5492171 | 0.77 | HSD11B1 (0.69) | CYP2C19HSD11B1SMN1; SMN2ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377528-A1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-07-11 | — | — | EP | disclosed |