Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749290 | 0.90 | MEN1 (0.44) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL22749289 | 0.90 | MEN1 (0.44) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29508380 | 0.90 | MEN1 (0.44) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL31411153 | 0.87 | LRRK2 (0.55) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL21995467 | 0.84 | MAPT (0.38) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL21995466 | 0.84 | MAPT (0.38) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL2086455 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9386488 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9388712 | 0.84 | MAPT (0.41) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL28684165 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914203-A | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |