Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749290 | 1.00 | MEN1 (0.44) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL22749289 | 1.00 | MEN1 (0.44) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10448992 | 0.90 | MAPT (0.42) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL31411153 | 0.89 | LRRK2 (0.55) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL29508391 | 0.87 | MEN1 (0.42) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10589261 | 0.84 | GALR3 (0.49) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1774882 | 0.84 | MAPT (0.42) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9386488 | 0.83 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2086455 | 0.83 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9388712 | 0.83 | MAPT (0.41) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |