Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120703 | 0.88 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4726732 | 0.85 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9836946 | 0.83 | KMT2A (0.46) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9388712 | 0.83 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4011205 | 0.82 | MEN1 (0.40) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1233747 | 0.81 | MEN1 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12547956 | 0.81 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27365630 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15923304 | 0.79 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1949343 | 0.79 | MEN1 (0.42) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914203-A | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |