Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675050 | 0.68 | KDM4E (0.43) | GAALMNAPKMMEN1KMT2A | |
| SCHEMBL17701198 | 0.68 | PTK2 (0.39) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL2150991 | 0.67 | ROCK2 (0.49) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL9316319 | 0.67 | PTK2 (0.42) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL17701220 | 0.65 | PTK2 (0.46) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL17701234 | 0.65 | ROCK2 (0.44) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL18437163 | 0.63 | HDAC8 (0.31) | — | |
| SCHEMBL17701212 | 0.63 | PTK2 (0.38) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL2151325 | 0.63 | ROCK2 (0.72) | PTK2NOTUMGAALMNAPKM | |
| SCHEMBL17701203 | 0.62 | PTK2 (0.41) | PTK2NOTUMGAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353667-A1 | Bithienyl derivatives, process for their preparation, and compositions containing them | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | claimed |