Ethoxyresorufin

Ethoxyresorufin

SCHEMBL104497

CCOc1ccc2nc3ccc(=O)cc-3oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 1.00
CYP1A2 P05177 2/20 1.00
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
F2RL3 Q96RI0 1/20 0.43
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxyresorufin SCHEMBL31079400 1.00 APP (1.00) APPCYP1A2CA12CA1CA4
SCHEMBL1104922 0.90 APP (0.82) APPCYP1A2CA12CA1CA4
SCHEMBL16069679 0.90 APP (0.81) APPCYP1A2CA12CA1CA4
SCHEMBL505449 0.88 APP (0.78) APPCYP1A2CA12CA1CA4
SCHEMBL31492097 0.88 APP (0.78) APPCYP1A2CA12CA1CA4
SCHEMBL1104925 0.87 APP (0.80) APPCYP1A2CA12CA1CA4
SCHEMBL10167880 0.86 APP (1.00) APPCYP1A2
SCHEMBL10167882 0.85 APP (1.00) APPCYP1A2
SCHEMBL563392 0.85 APP (1.00) APPCYP1A2CA12CA1CA4
SCHEMBL31115697 0.85 APP (1.00) APPCYP1A2CA12CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250093331-A1 METHOD FOR DETERMINING ACUTE TOXICITY AND A SYSTEM USING SAID METHOD CITY UNIVERSITY OF HONG KONG (HK) 2025-03-20 US claimed
US-12098391-B2 Generation of hepatocytes from pluripotent stem cells ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2024-09-24 US claimed
CN-107478816-A Poison test for cosmetic products 水中银(国际)生物科技有限公司 2017-12-15 CN claimed
CN-103487412-B Method for constructing rapid hepatotoxicity predication model of phenolic compound UNIV SHANGHAI JIAOTONG 2015-07-15 CN claimed
CN-103487412-A Method for constructing rapid hepatotoxicity predication model of phenolic compound UNIV SHANGHAI JIAOTONG 2014-01-01 CN claimed
US-20050215533-A1 Method to inhibit ischemia and reperfusion injury RADICAL THERAPEUTIX 2005-09-29 US claimed
EP-0649472-B1 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE UNIV TEXAS (US) 2003-12-10 EP claimed
EP-1083223-A1 NOVEL IMMORTALIZED HEPATIC CELL LINE ORIGINATING IN HUMANS Takeda Chemical Industries, Ltd. (JP) 2001-03-14 EP claimed
EP-0649472-A4 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE. UNIV TEXAS (US) 1997-03-19 EP claimed
EP-0649472-A1 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-04-26 EP claimed
WO-1994001568-A1 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-01-20 WO claimed
WO-1992013076-A1 METHODS AND COMPOSITIONS FOR THE EXPRESSION OF BIOLOGICALLY ACTIVE EUKARYOTIC CYTOCHROME P450S IN BACTERIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-08-06 WO claimed
US-4865972-A Antibody-based bioassay for enzyme-inducing chemicals WESTINGHOUSE ELECTRIC CORP. (US) 1989-09-12 US claimed
EP-0259073-A2 Antibody-based bioassays for enzyme-inducing chemicals WESTINGHOUSE ELECTRIC CORPORATION (US) 1988-03-09 EP claimed
US-12606560-B1 Method of converting mitragynine to 7-hydroxymitragynine MITCHELL HAYWOOD MAX (US) 2026-04-21 US disclosed
US-20260097037-A1 FUSED RING COMPOUND HAVING GLP-1 RECEPTOR AGONIST EFFECT SHIONOGI & CO., LTD. (JP) 2026-04-09 US disclosed
US-20260098031-A1 MONOCYCLIC COMPOUND HAVING GLP-1 RECEPTOR AGONIST ACTIVITY SHIONOGI & CO., LTD. (JP) 2026-04-09 US disclosed
EP-0259073-A2 Antibody-based bioassays for enzyme-inducing chemicals WESTINGHOUSE ELECTRIC CORPORATION (US) 1988-03-09 EP disclosed
US-4599901-A Pressure-sensitive optrode UNIVERSITY OF CALIFORNIA (US) 1986-07-15 US disclosed
EP-0183329-A2 Pressure-sensitive optrode THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1986-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098031-A1 MONOCYCLIC COMPOUND HAVING GLP-1 RECEPTOR AGONIST ACTIVITY GLP1R, GCGR, CCKAR APP 3917/4885CYP1A2 3925/4885CA12 2495/4885
US-20260097037-A1 FUSED RING COMPOUND HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, CCKAR, GCGR APP 3879/4885CYP1A2 3450/4885CA12 3023/4885
US-12606560-B1 Method of converting mitragynine to 7-hydroxymitragynine LIPA, DHCR7, VAMP7 APP 4783/4885CYP1A2 1373/4885CA12 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.