Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492097 | 1.00 | APP (0.78) | APPCYP1A2CA12CA1CA2 | |
| SCHEMBL16069679 | 0.98 | APP (0.81) | APPCYP1A2CA12CA1CA2 | |
| SCHEMBL1104928 | 0.91 | APP (0.69) | APPCYP1A2CA12CA1CA2 | |
| Ethoxyresorufin SCHEMBL104497 | 0.88 | APP (1.00) | APPCYP1A2CA12CA1CA6 | |
| Ethoxyresorufin SCHEMBL31079400 | 0.88 | APP (1.00) | APPCYP1A2CA12CA1CA6 | |
| SCHEMBL10167880 | 0.87 | APP (1.00) | APPCYP1A2 | |
| SCHEMBL16196000 | 0.87 | APP (0.80) | APPCYP1A2CA12CA1CA2 | |
| SCHEMBL10167882 | 0.86 | APP (1.00) | APPCYP1A2 | |
| SCHEMBL10167874 | 0.85 | APP (1.00) | APPCYP1A2 | |
| SCHEMBL23625199 | 0.84 | APP (0.71) | APPCYP1A2CA12CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-113293150-A | Mutant enzymes | 牛津大学科技创新有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-105441397-B | Mutant enzymes | 牛津大学科技创新有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-10638734-B2 | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof | ABT HOLDING COMPANY (US) | 2020-05-05 | — | — | US | disclosed |
| CN-105467765-B | Photosensitive composition, method for producing cured film, and use thereof | 富士胶片株式会社 | 2020-04-24 | — | — | CN | disclosed |
| CN-105467766-B | Curable composition, cured film, organic electroluminescent display device, liquid crystal display device, and touch panel display device | 富士胶片株式会社 | 2020-04-07 | — | — | CN | disclosed |
| CN-106575078-B | Photosensitive composition, cured film and method for producing the same, touch panel and display device thereof, liquid crystal display device, and organic EL display device | 富士胶片株式会社 | 2020-02-21 | — | — | CN | disclosed |
| US-10495631-B2 | In vitro model of macrosteatotic (fatty) liver | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-12-03 | — | — | US | disclosed |
| US-10286421-B2 | Photosensitive composition, method for producing cured product, cured film, display device, and touch panel | FUJIFILM CORPORATION (JP) | 2019-05-14 | — | — | US | disclosed |
| US-5849727-A | Compositions and methods for altering the biodistribution of biological agents | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-12-15 | — | — | US | disclosed |
| WO-1998003171-A2 | USE OF INHIBITORS OF CYP2A6 FOR REGULATING NICOTINE METABOLISM | NICOGEN INC. (CA) | 1998-01-29 | — | — | WO | disclosed |
| WO-1997043448-A2 | ANALYSIS OF EXPRESSION OF RAT CYTOCHROME P450 ISOENZYMES AND PHASE II CONJUGATING ENZYMES | G.D. SEARLE & CO. (US) | 1997-11-20 | — | — | WO | disclosed |
| WO-1997035994-A2 | CYTOCHROME P450 TRANSDUCING RETROVIRAL VECTORS | BAVARIAN NORDIC RESEARCH INSTITUTE A/S (DK) | 1997-10-02 | — | — | WO | disclosed |
| WO-1996001426-A1 | HEPATOCYTE TEST KIT | W.R. GRACE & CO.-CONN. (US) | 1996-01-18 | — | — | WO | disclosed |
| US-5474757-A | Administering diallyl sulfone to prevent metabolism of acetaminophen into hepatotoxic metabolites | RUTGERS UNIVERSITY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1994008628-A1 | PREVENTION OF ACETAMINOPHEN OVERDOSE TOXICITY WITH ORGANOSULFUR COMPOUNDS | RUTGERS UNIVERSITY (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5242805-A | Useful in directingcells producing enzymes that hydrolyze the glycoside | MOLECULAR PROBES, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993004074-A1 | LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1992014817-A1 | IN VIVO ASSAY SYSTEMS FOR METABOLIC ROUTES | IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | APP 3721/4885CYP1A2 2469/4885CA12 3185/4885 |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | APP 3490/4885CYP1A2 4154/4885CA12 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.