Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452374 | 0.78 | MAPT (0.46) | MAPTNPC1HTTRAB9AL3MBTL1 | |
| SCHEMBL1157660 | 0.77 | MAPT (0.55) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL9799523 | 0.77 | MAPT (0.55) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL1462546 | 0.75 | MAPT (0.56) | MAPTNPC1HTTRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11851685 | 0.73 | MAPT (0.54) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL4052304 | 0.73 | MAPT (0.54) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL11662147 | 0.72 | MAPT (0.53) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL11226102 | 0.72 | MAPT (0.54) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL216700 | 0.72 | MAPT (0.58) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL23088064 | 0.71 | MAPT (0.52) | MAPTNPC1HTTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202054-B1 | PRODUCTION OF S-ARYL S-ALKYL DITHIOCARBONATES, ARENETHIOLS AND ARYTHIOETHERS | COURTAULDS PLC (GB) | 1990-07-25 | — | — | EP | disclosed |
| US-4711967-A | PYROLYTICALLY ISOMERIZING AND O-ARYL S-ALKYL DITHIOCARBONATE | COURTAULDS PLC (GB) | 1987-12-08 | — | — | US | disclosed |
| EP-0202054-A1 | Production of S-aryl S-alkyl dithiocarbonates, arenethiols and arythioethers | COURTAULDS PLC (GB) | 1986-11-20 | — | — | EP | disclosed |