SCHEMBL9799523

SCHEMBL9799523

CC(=O)Sc1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NPC1 O15118 1/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
LMNA P02545 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 2/20 0.44
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
BRD4 O60885 1/20 0.42
TERT O14746 1/20 0.41
TSHR P16473 2/20 0.41
MMP2 P08253 1/20 0.41
MMP8 P22894 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1157660 1.00 MAPT (0.55) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL14341653 0.87 HPGD (0.46) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL216700 0.80 MAPT (0.58) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL14367054 0.80 L3MBTL1 (0.41) MAPTL3MBTL1HTTLMNAHSD17B10
SCHEMBL4828988 0.79 MAPT (0.49) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL9596657 0.78 SRD5A2 (0.53) MAPTLMNA
SCHEMBL1462546 0.78 MAPT (0.56) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL6208993 0.78 NR1H2 (0.48) MAPTL3MBTL1NPC1HTTRAB9A
SCHEMBL7518002 0.78 MAPT (0.50) MAPTL3MBTL1HTTNPSR1LMNA
SCHEMBL11410221 0.78 MAPT (0.55) MAPTL3MBTL1NPC1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed