Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438853 | 1.00 | DGKA (0.58) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL27681316 | 0.95 | PRSS1 (0.64) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL4106139 | 0.93 | DGKA (0.52) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11443788 | 0.92 | DGKA (0.55) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL10392177 | 0.90 | PRSS1 (0.51) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11577455 | 0.90 | PRSS1 (0.51) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL15976529 | 0.89 | DGKA (0.65) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL10451052 | 0.88 | DGKA (0.48) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL10481986 | 0.88 | PRSS1 (0.49) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL9569406 | 0.87 | DGKA (0.61) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4871864-A | Carbamoyloxythiophene fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4839381-A | FUNGICIDES, PESTICIDES; RICE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0243776-A2 | Carbamoyloxythiophene derivatives | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |
| US-4243611-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4228104-A | PROSTAGLANDIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| EP-0000023-B1 | OMEGA-SUBSTITUTED PENTYL UREAS, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |