Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452417 | 0.83 | NPC1 (0.39) | NPC1RAB9AKMT2ALMNAHTT | |
| SCHEMBL7943850 | 0.78 | KDM4E (0.46) | KMT2ALMNAKDM4EPOLBCHRM3 | |
| SCHEMBL10335699 | 0.73 | NPC1 (0.43) | NPC1RAB9ABCL2KMT2ANPSR1 | |
| SCHEMBL11670898 | 0.72 | KDM4E (0.45) | LMNAKDM4EPOLBKIF11SLC6A2 | |
| SCHEMBL9177845 | 0.71 | TSHR (0.43) | KMT2AKDM4EPTPN1MEN1MAPT | |
| SCHEMBL26592456 | 0.71 | ALDH1A1 (0.38) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL10334686 | 0.71 | PPARA (0.50) | NPC1RAB9AKMT2ANPSR1LMNA | |
| SCHEMBL26592483 | 0.70 | IDO1 (0.38) | NPC1RAB9AKMT2ANPSR1LMNA | |
| SCHEMBL16587991 | 0.68 | TSHR (0.40) | KMT2AMEN1 | |
| SCHEMBL18525626 | 0.68 | TSHR (0.43) | SLC6A2PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |