⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686147 | 1.00 | — | — | |
| SCHEMBL28686149 | 0.80 | — | — | |
| SCHEMBL10453087 | 0.80 | — | — | |
| SCHEMBL26071568 | 0.77 | — | — | |
| SCHEMBL28891788 | 0.76 | — | — | |
| SCHEMBL28672078 | 0.76 | — | — | |
| SCHEMBL3362081 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL9634696 | 0.72 | — | — | |
| SCHEMBL9633636 | 0.72 | — | — | |
| SCHEMBL9863090 | 0.71 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937367-A | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.P.A. (IT) | 1990-06-26 | — | — | US | disclosed |
| EP-0299484-A1 | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.p.A. (IT) | 1989-01-18 | — | — | EP | disclosed |