⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618445 | 1.00 | — | — | |
| SCHEMBL9634515 | 1.00 | — | — | |
| Imidazole SCHEMBL10964559 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL4931916 | 0.78 | — | — | |
| SCHEMBL9634513 | 0.78 | — | — | |
| SCHEMBL11395390 | 0.78 | — | — | |
| SCHEMBL30834175 | 0.72 | — | — | |
| SCHEMBL22393562 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL19940053 | 0.69 | — | — | |
| SCHEMBL18257899 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969758-B2 | Antimicrobial compounds | BIOMERIEUX (FR) | 2018-05-15 | — | — | US | disclosed |
| US-20170158720-A1 | Antimicrobial Compounds | BIOMERIEUX (FR) | 2017-06-08 | — | — | US | disclosed |
| US-4937367-A | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.P.A. (IT) | 1990-06-26 | — | — | US | disclosed |
| EP-0299484-A1 | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.p.A. (IT) | 1989-01-18 | — | — | EP | disclosed |
| EP-0027597-A1 | Mono(2-ammonium-2-hydroxymethyl-1,3-propanediol)(2R-cis)-(3-methyloxiranyl)phosphonate, its preparation and pharmaceutical compositions containing it | ZAMBON S.p.A. (IT) | 1981-04-29 | — | — | EP | disclosed |