Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453218 | 0.76 | TSHR (0.46) | MAPK1CYP3A4TSHRTDP1HTT | |
| SCHEMBL10363437 | 0.74 | CYP3A4 (0.40) | CYP3A4TDP1LMNAMEN1KMT2A | |
| SCHEMBL9836602 | 0.73 | TDP1 (0.43) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL6570416 | 0.71 | TSHR (0.44) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL9835486 | 0.71 | TDP1 (0.41) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL28990592 | 0.68 | SMN1; SMN2 (0.37) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL28990685 | 0.68 | SMN1; SMN2 (0.37) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL9834535 | 0.68 | TDP1 (0.38) | MAPK1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL10453197 | 0.68 | TDP1 (0.38) | MAPK1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL10453159 | 0.68 | OGG1 (0.46) | MAPK1CYP3A4TSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |