Sugi Predict
/ Targets
/ OGG1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to OGG1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Microsatellite Stable, MGMT Silenced Metastatic Colorectal Cancer |
PHASE2 | COMPLETED |
| Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL) |
PHASE2 | COMPLETED |
| Satraplatin and Prednisone to Treat Prostate Cancer |
PHASE2 | COMPLETED |
| A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas |
PHASE2 | UNKNOWN |
| Olaparib in People With Malignant Mesothelioma |
PHASE2 | COMPLETED |
| Phase II ABT-888 With Cyclophosphamide |
PHASE2 | COMPLETED |
| Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) |
PHASE2 | UNKNOWN |
| A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies |
PHASE1/PHASE2 | RECRUITING |
| Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC) |
PHASE2 | NOT_YET_RECRUITING |
| N-Acetylcysteine Protection Against Radiation Induced Cellular Damage |
PHASE2 | COMPLETED |
| Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17) |
PHASE1/PHASE2 | UNKNOWN |
| Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients |
PHASE2 | COMPLETED |
| Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer |
PHASE2 | RECRUITING |
| Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma |
PHASE1 | RECRUITING |
| A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors |
PHASE1 | COMPLETED |
| Application of Genetic Polymorphisms of DNA Repair in The Prediction of Prostate Cancer Susceptibility and Its Clinical Outcome |
nan | UNKNOWN |
| Expression of TET1 Gene in Acute Leukaemia |
nan | UNKNOWN |
| DNA Repair Genes and Outcomes in Patients With Stage III NSCLC |
nan | UNKNOWN |
| DNA Adductomics for Colorectal Cancer Investigation |
nan | UNKNOWN |
| Environmental Pollutants in COPD and Lung Cancer |
nan | RECRUITING |
| A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients |
nan | COMPLETED |
| Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients |
nan | COMPLETED |
| Effects of Resistance Training Programes At Different Intensities on Musculoskeletal, Metabolic, Lipid, Immunological, Inflammatory, Well-being and Functional Parameters in Older Adults. |
nan | COMPLETED |
| Comparison of Oxidants and Antioxidants in Breastmilk Under Different Anesthesia Protocols |
nan | COMPLETED |
| Immunohistochemical Expression of Excision Repair Cross Complementation Group 1 (ERCC1) in Laryngeal Squamous Cell Carcinoma and Its Correlation With Response to Radiotherapy. |
nan | UNKNOWN |
| Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews |
nan | COMPLETED |
| Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 |
nan | COMPLETED |
| Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazine Treated Sarcoma Patients (MGMT) |
nan | UNKNOWN |
| Vascular Senescence and Atherosclerotic Plaque Vulnerability |
nan | RECRUITING |
Related proteins — ESM-2 sequence neighbours (a OGG1 binder may also engage these)