⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475284 | 0.78 | — | — | |
| SCHEMBL1942558 | 0.78 | — | — | |
| SCHEMBL988920 | 0.77 | LMNA (0.39) | — | |
| SCHEMBL7197208 | 0.73 | — | — | |
| SCHEMBL105067 | 0.72 | — | — | |
| SCHEMBL11199752 | 0.72 | — | — | |
| SCHEMBL167808 | 0.69 | — | — | |
| SCHEMBL11312587 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL18134583 | 0.69 | — | — | |
| SCHEMBL4283553 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331133-A | Sulphonamidoaniline derivatives as Janus kinase inhibitors | NOVARTIS AG (CH) | 2008-12-24 | — | — | CN | claimed |
| US-20080261973-A1 | Sulphonamidoaniline Derivatives Being Janus Kinase Inhibitors | NOVARTIS AG (CH) | 2008-10-23 | — | — | US | claimed |
| EP-1966210-A2 | SULPHONAMIDOANILINE DERIVATIVES BEING JANUS KINASES INHIBITORS | Novartis AG (CH) | 2008-09-10 | — | — | EP | claimed |
| WO-2007071393-A2 | SULPHONAMIDOANILINE DERIVATIVES BEING JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | claimed |
| CN-116783204-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20230190730-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT | JAPAN TOBACCO INC. (JP) | 2023-06-22 | — | — | US | disclosed |
| WO-2021121327-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| US-20200101061-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT | JAPAN TOBACCO INC. (JP) | 2020-04-02 | — | — | US | disclosed |
| EP-3406596-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR | Japan Tobacco Inc. (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-3405166-A1 | HYDROPHOBIC TOPICAL COMPOSITIONS | Edgewell Personal Care Brands, LLC (US) | 2018-11-28 | — | — | EP | disclosed |
| US-20180265454-A1 | Method for Producing 4-Oxoquinoline Compound | JAPAN TOBACCO INC. (JP) | 2018-09-20 | — | — | US | disclosed |
| EP-2750657-B1 | BISUREA GELLING AGENTS AND COMPOSITIONS | MILLIKEN & CO (US) | 2018-03-21 | — | — | EP | disclosed |
| WO-1998027950-A1 | ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027949-A1 | ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027951-A2 | ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS SUBSTANTIALLY FREE OF SELECT POLAR SOLVENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027955-A1 | ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998028008-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING GELLANTS IN THE FORM OF ALKYL AMIDES OF DI- AND TRI-CARBOXYLIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027952-A1 | METHODS OF MAKING LOW RESIDUE ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| US-5750096-A | SOLID NON-POLYMERIC GELLANT BASED ON 12-HYDROXYSTEARIC ACID; ANHYDROUS LIQUID CARRIER | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5744130-A | COMPRISING ACTIVE MATERIAL, NONPOLYMERIC GELLANT, ANHYDROUS LIQUID CARRIER; LOW RESIDUE | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-28 | — | — | US | disclosed |