SCHEMBL10453603

SCHEMBL10453603

CCCCc1cc(CCCC)c(Cl)c(C)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.40
TYR P14679 3/20 0.39
HTT P42858 4/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
SKP2 Q13309 1/20 0.34
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TLR8 Q9NR97 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10454847 0.90 CTRC (0.37) CTRCTYRHTTNPC1HPGD
SCHEMBL10446044 0.86 HTT (0.42) CTRCTYRHTTNPC1HPGD
Phosphine SCHEMBL9358676 0.84 HTT (0.41) CTRCTYRHTTNPC1HPGD
Hydrochloric Acid SCHEMBL8830012 0.83 HPGD (0.39) CTRCTYRHTTNPC1HPGD
SCHEMBL9073055 0.78 CTRC (0.46) CTRCTYRHTTNPC1HPGD
SCHEMBL11682168 0.77 TYR (0.50) CTRCTYRHTTNPC1HPGD
SCHEMBL8089722 0.77 CTRC (0.37) CTRCTYRHTTNPC1HPGD
SCHEMBL8089662 0.77 CTRC (0.44) CTRCTYRHTTHPGDNPSR1
SCHEMBL5589280 0.77 TYR (0.44) CTRCTYRHTTNPC1HPGD
SCHEMBL10157301 0.77 CTRC (0.49) CTRCTYRHTTHPGDSKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2101030-A None JP disclosed
JP-H02101030-A PRODUCTION OF 5-BUTYL-2,3,6-TRICHLOROTOLUENE IDEMITSU KOSAN CO LTD 1990-04-12 JP disclosed