Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985719 | 0.91 | GRM5 (0.34) | GRM5AAK1ROCK2LMNAGAA | |
| SCHEMBL803206 | 0.79 | MAOB (0.58) | GRM5ROCK2 | |
| SCHEMBL19566332 | 0.79 | GRM5 (0.49) | GRM5LMNAGAAMAPTBACE1 | |
| SCHEMBL10454621 | 0.77 | AAK1 (0.35) | GRM5AAK1ROCK2MAPT | |
| SCHEMBL18462455 | 0.75 | ROCK2 (0.34) | GRM5AAK1ROCK2LMNAMAPT | |
| SCHEMBL18462718 | 0.75 | AAK1 (0.33) | GRM5AAK1ROCK2BACE1 | |
| SCHEMBL2707367 | 0.74 | PRMT5 (0.33) | GRM5AAK1ROCK2LMNA | |
| SCHEMBL10454700 | 0.74 | AAK1 (0.33) | AAK1ROCK2MAPT | |
| SCHEMBL2708388 | 0.74 | AAK1 (0.35) | GRM5AAK1ROCK2MAPT | |
| SCHEMBL4656696 | 0.69 | CYP3A4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940184-B2 | Polymerizable compounds and their use in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, ACP3 | GRM5 2001/4885AAK1 1438/4885ROCK2 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.