Biphenyl

Biphenyl

SCHEMBL10455231

[Zr]C1C=Cc2ccccc21.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HTR2A P28223 2/20 0.36
HTR6 P50406 1/20 0.36
SIGMAR1 Q99720 6/20 0.33
CYP3A4 P08684 2/20 0.30
HSD17B10 Q99714 2/20 0.30
MAPK1 P28482 1/20 0.30
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814489 0.91 HTR2A (0.41) ALDH1A1HTR2AHTR6SIGMAR1CYP3A4
SCHEMBL29758183 0.91 HTR2A (0.41) ALDH1A1HTR2AHTR6SIGMAR1CYP3A4
SCHEMBL16296388 0.91 HTR2A (0.41) ALDH1A1HTR2AHTR6SIGMAR1CYP3A4
Hydrochloric Acid SCHEMBL812666 0.89 HTR2A (0.40) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Bromide SCHEMBL6903238 0.89 HTR2A (0.40) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Hydrochloric Acid SCHEMBL7250686 0.89 HTR2A (0.40) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Hydrochloric Acid SCHEMBL5709238 0.89 HTR2A (0.40) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Hydrochloric Acid SCHEMBL28723796 0.89 HTR2A (0.40) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Chloromethane SCHEMBL8149410 0.85 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP3A4HSD17B10
Methylamine SCHEMBL27634217 0.85 HTR2A (0.42) ALDH1A1HTR2AHTR6SIGMAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366290-A2 Process for producing olefin polymers CHISSO CORPORATION (JP) 1990-05-02 EP claimed
EP-0366290-A2 Process for producing olefin polymers CHISSO CORPORATION (JP) 1990-05-02 EP disclosed