SCHEMBL814489

SCHEMBL814489

[Zr]C1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.41
HTR6 P50406 1/20 0.40
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 3/20 0.33
CYP2D6 P10635 2/20 0.33
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 2/20 0.33
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758183 1.00 HTR2A (0.41) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL16296388 1.00 HTR2A (0.41) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL28723796 0.98 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL812666 0.98 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Bromide SCHEMBL6903238 0.98 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL5709238 0.98 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL7250686 0.98 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Methyl Alcohol SCHEMBL8383611 0.93 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Chloromethane SCHEMBL8149410 0.93 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Biphenyl SCHEMBL10455231 0.91 ALDH1A1 (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710502-A1 POLYMERIZATION PROCESSES ExxonMobil Chemical Patents Inc. (US) 2020-09-23 EP claimed
CN-1738678-A Alkene tandem type tetramer-polymerization method SASOL TECH PTY LTD (ZA) 2006-02-22 CN claimed
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP claimed
EP-0776908-B1 Catalyst composition having improved comonomer reactivity UNIVATION TECH LLC (US) 2001-07-11 EP claimed
US-6028151-A Catalyst composition having improved comonomer reactivity UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-02-22 US claimed
US-5756416-A COORDINATION CATALYST FOR OLEFIN POLYMERIZATION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-05-26 US claimed
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0776908-A1 Catalyst composition having improved comonomer reactivity UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-06-04 EP claimed
EP-0422703-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS Enichem Anic S.r.l. (IT) 1993-06-30 EP claimed
EP-4127039-B1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
EP-4251696-B1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
US-20240376302-A1 ASA-COPOLYMER COMPOSITIONS WITH INCREASED TRANSMITTANCE AND PROCESS FOR THE PREPARATION THEREOF INEOS STYROLUTION GROUP GMBH (DE) 2024-11-14 US disclosed
US-20240317968-A1 HIGH CLARITY AND LOW HAZE UV STABILIZED STYRENE AND METHYL METHACRYLATE COPOLYMERS INEOS STYROLUTION GROUP GMBH (DE) 2024-09-26 US disclosed
EP-4402208-A1 ASA-COPOLYMER COMPOSITIONS WITH INCREASED TRANSMITTANCE AND PROCESS FOR THE PREPARATION THEREOF INEOS Styrolution Group GmbH (DE) 2024-07-24 EP disclosed
US-5455316-A Polymerizing or copolymerizing olefins in presence of solid catalyst consisting of aluminoxane and transition metal compound containing cyclopentadienyl skeleton supported on silica particulate carrier MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-10-03 US disclosed
CN-1108275-A Polymer alloy HOECHST AG (DE) 1995-09-13 CN disclosed
US-5412128-A Catalyst for olefin polymerization, process for the polymerization of olefin, and transition metal compound employable for the catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-05-02 US disclosed
US-5409874-A Containing transition metal compound having cyclopentadienyl skeleton and sulfonate group, aluminoxane or benzene insoluble organoaluminum compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-04-25 US disclosed
CN-1096521-A Flexible cycloolefin copolymer film HOECHST AG (DE) 1994-12-21 CN disclosed
US-5346925-A Method for producing α-olefin polymers MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1994-09-13 US disclosed