SCHEMBL10455276

SCHEMBL10455276

Cc1ccccc1OP(O)(O)=S

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 2/20 0.40
CYP1A2 P05177 2/20 0.39
ALDH1A1 P00352 1/20 0.39
NOTUM Q6P988 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ACHE P22303 1/20 0.38
MAPT P10636 1/20 0.37
SRC P12931 1/20 0.37
LMNA P02545 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PPARG P37231 1/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320756 0.87 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL8469167 0.83 MAPT (0.56) MEN1KMT2ANPC1RAB9AKDM4E
SCHEMBL29581117 0.82 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL7100690 0.82 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28299991 0.82 KDM4E (0.37) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28052034 0.81 SRC (0.42) MEN1KMT2ASMN1; SMN2KDM4ECYP1A2
SCHEMBL28286381 0.80 KDM4E (0.36) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29247987 0.78 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL5851928 0.78 MAPT (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL1100136 0.78 INPPL1 (0.57) KDM4ECYP1A2ALDH1A1NOTUMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452498-A A kind of preparation method of wear-resisting automatically cleaning Plastic overshoes material JIESHOU HONGXIN PLASTIC IND CO LTD 2019-11-15 CN claimed
CN-107880854-B Composite phase change cold storage material and preparation method thereof 大连理工大学 2019-08-09 CN claimed
CN-109912657-A Fire retardant tri o cresyl thiophosphate (the thio phosphono heterocycle methylene of silicon) ester compounds and preparation method thereof 苏州科技大学 2019-06-21 CN claimed
CN-109880168-A Fire retardant tricresyl phosphate (dimethyl-silicon phosphono heterocycle methylene) ester compounds and preparation method thereof 苏州科技大学 2019-06-14 CN claimed
CN-109824733-A Fire retardant tri o cresyl thiophosphate (dimethyl-silicon phosphono heterocycle methylene) ester compounds and preparation method thereof 苏州科技大学 2019-05-31 CN claimed
CN-109810144-A Fire retardant tricresyl phosphate (the thio phosphono heterocycle methylene of dimethyl-silicon) ester compounds and preparation method thereof 苏州科技大学 2019-05-28 CN claimed
CN-109796575-A The preparation method and applications of stabilizer and preparation method thereof, polymer polyatomic alcohol 万华化学集团股份有限公司 2019-05-24 CN claimed
CN-109705604-A A kind of flame retardant automotive foot pad material and preparation method thereof 浙江炬利汽车零部件有限公司 2019-05-03 CN claimed
CN-109585920-A Lithium ion battery and its electrolyte 欣旺达电子股份有限公司 2019-04-05 CN claimed
CN-106833358-B The multifunctional polyurethane acrylate composition of dual cure 淮海工学院 2019-03-29 CN claimed
CN-1256359-C Monomer-free reactive polyurethane adhesion promoters HENKEL KGAA (DE) 2006-05-17 CN claimed
CN-1224479-C Mathod for preparing micro powder containing anti-agglomerated nanometer silver, micro powder produced by the mathod and its application SHENZHEN TSINGHUA YUANXING NAN (CN) 2005-10-26 CN claimed
CN-1627901-A Nano composite material of silver TSINGHUA YUANXING BIOMEDICINE (CN) 2005-06-15 CN claimed
CN-1568337-A Reactive polyurethane compositions with a low residual monomer content HENKEL KGAA (DE) 2005-01-19 CN claimed
CN-1522295-A Lubricating oil composition comprising an additive combination of a carboxylic acid and an amine as ant-rust agent ���ʿ����о����޹�˾ 2004-08-18 CN claimed
CN-1505551-A Preparation method of anti-aggregation nano silver, micro powder containing anti-aggregation nano silver prepared by method and application of micro powder �������廪Դ�����ײ������޹�˾ 2004-06-16 CN claimed
CN-1402742-A Adhesion promoters for monomer-free reactive polyurethanes HENKEL KGAA (DE) 2003-03-12 CN claimed
CN-1057557-C Refrigerating machine oil composite used together with hydrogen-chlorine-fluoro hydrocarbon and hydrogen-chlorine refrigerating agent MITSUBISHI HEAVY IND LTD (JP) 2000-10-18 CN claimed
CN-1032040-C Mixed fungicidal and insecticidal composition BAYER AGROCHEM KK (JP) 1996-06-19 CN claimed
CN-1060577-A Fungicide and insecticidal composition BAYER AGROCHEM KK (JP) 1992-04-29 CN claimed