SCHEMBL7100690

SCHEMBL7100690

Cc1ccccc1OP(=S)(Oc1ccccc1C)Oc1ccccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ACHE P22303 1/20 0.41
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.38
GLA P06280 1/20 0.38
CYP1A2 P05177 3/20 0.38
NOTUM Q6P988 1/20 0.37
SCN4A P35499 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581117 1.00 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL27650203 0.90 DRD2 (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL5851935 0.87 TSHR (0.38) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL5851928 0.82 MAPT (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29247987 0.82 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28181743 0.82 MAPT (0.46) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL30320756 0.82 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL3341056 0.82 MAPT (0.60) MEN1KMT2ARAB9AKDM4EMAPT
SCHEMBL29365600 0.82 MAPT (0.60) MEN1KMT2ARAB9AKDM4EMAPT
SCHEMBL789909 0.82 KMT2A (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0931828-B1 Lubricant composition for refrigerating machine employing hydrofluorocarbon as refrigerant MITSUBISHI ELECTRIC CORP (JP) 2003-09-17 EP claimed
EP-0931828-A2 Lubricant composition for refrigerating machine employing hydrofluorocarbon as refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1999-07-28 EP claimed
EP-0176022-B1 FLAME RETARDANT POLYPHENYLENE OXIDE THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1989-09-06 EP claimed
EP-0175281-B1 FLAME RETARDANT POLYPHENYLENE OXIDE THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1989-08-09 EP claimed
US-4593058-A Containing an organothiophosphate GENERAL ELECTRIC COMPANY (US) 1986-06-03 US claimed
US-4584332-A BLEND WITH STYRENE RESIN, ZINC OXIDE, AND ORGANOTHIOPHOSPHATE GENERAL ELECTRIC COMPANY (US) 1986-04-22 US claimed
EP-0176022-A2 Flame retardant polyphenylene oxide thermoplastics GENERAL ELECTRIC COMPANY (US) 1986-04-02 EP claimed
EP-0175281-A2 Flame retardant polyphenylene oxide thermoplastics GENERAL ELECTRIC COMPANY (US) 1986-03-26 EP claimed
US-3954877-A GROUP VIII METAL COMPLEX CATALYST JEFFERSON CHEMICAL CO., INC. (US) 1976-05-04 US claimed
CN-113004323-B Method for preparing phosphate ester derivatives from white phosphorus 厦门大学 2022-04-01 CN disclosed
CN-113004323-A Method for preparing phosphate ester derivatives from white phosphorus 厦门大学 2021-06-22 CN disclosed
EP-0931828-B1 Lubricant composition for refrigerating machine employing hydrofluorocarbon as refrigerant MITSUBISHI ELECTRIC CORP (JP) 2003-09-17 EP disclosed
EP-0931828-A2 Lubricant composition for refrigerating machine employing hydrofluorocarbon as refrigerant MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1999-07-28 EP disclosed
US-4257958-A INORGANIC BORON-OXYGEN COMPOUND ADDITIVES TEXACO INC. (US) 1981-03-24 US disclosed
US-3954877-A GROUP VIII METAL COMPLEX CATALYST JEFFERSON CHEMICAL CO., INC. (US) 1976-05-04 US disclosed